Physicians/Specialists
Facilities/Hospitals
Pharmacy
Publication Date: 
2022-01-27

Blue Cross and Blue Shield of North Carolina (Blue Cross NC) will apply the following new requirements to our pharmacy utilization management for the below listed drugs. These changes will be effective April 1, 2022. 

Our utilization management requirements apply to all commercial members with pharmacy benefit coverage through Blue Cross NC. These changes will not apply to the following lines of business:  State Health Plan, Federal Employee Program, Medicare Part D members, or any self-funded employer groups that carve out pharmacy benefits to another pharmacy benefits manager (PBM).  

Below is a summary of the changes, and more details can be found here.  

New Requirements 

IMPACTED MEDICATIONS  REQUIREMENT 
Lantus  This medication will require Step Therapy on all formularies. Brand Semglee (biosimilar) will be preferred.   
Carbaglu  This medication will require Prior Authorization on all formularies.  
Januvia, Janumet, Janumet XR, Jentadueto, Jentadueto XR, Kazano, Kombiglyze XR, Nesina, Onglyza, Oseni, Tradjenta  These medications and their generics (if applicable) will require Quantity Limits on all formularies.  
Farxiga, Glyxambi, Invokamet, Invokamet XR, Invokana, Jardiance, Qtern, Segluromet, Steglatro, Steglujan, Synjardy, Synjardy XR, Trijardy XR, Xigduo XR  These medications and their generics (if applicable) will require Quantity Limits on all formularies.  
Aptivus, Atripa, Biktarvy, Cimduo, Complera, Crixivan, Delstrigo, Descovy, Dovato, Edurant, Emtriva, Evotaz, Fuzeon, Genvoya, Intelence, Invirase, Isentress, Isentress HD, Juluca, Kaletra, Lexiva, Norvir, Odefsey, Pifeltro, Prezocobix, Presizta, Rescriptor, Reyataz, Rukobia, Selzentry, Stribild, Symfi, Symfi Lo, Symtuza, Tivicay, Tivicay PD, Triumeq, Truvada, Tybost, Videx, Videx EC, Viracept, Viramune, Viread, Retrovir  These medications and their generics (if applicable) will require Quantity Limits on all formularies.  
Kalydeco, Orkambi, Symdeko, Trikafta  These medications and their generics (if applicable) will require Quantity Limits on all formularies.  
Eliquis, Pradaxa, Savaysa, Xarelto  These medications and their generics (if applicable) will require Quantity Limits on all formularies.  
Cetrotide, Follistim AQ, Granirelix AC, Gonal-F, Menopur, Novarel, Ovidrel  These medications and their generics (if applicable) will require Quantity Limits on all formularies.  
Oxbryta  This medication will require Quantity Limits on all formularies.  
Advate, Adynovate, Afstyla, AlphaNine SD, Alprolix, Bebulin, BeneFIX, Eloctate, Esperoct, Helixate FS, Hemofil M, Idelvion, Ixinity, Jivi, Koāte/Koāte-DVI, Kogenate FS, Kovaltry, Mononine, NovoEight, Nuwiq, Profilnine, Rebinyn, Recombinate, Vonvendi, Wilate, Xyntha/Xyntha Solofuse–  These medications and their generics (if applicable) will require Quantity Limits on all formularies.

If you have any questions, please call the Provider Blue Line at 1-800-214-4844.