Physicians/Specialists
Facilities/Hospitals
Pharmacy
Publication Date: 
2022-11-03

Effective January 1, 2023, Blue Cross and Blue Shield of North Carolina (Blue Cross NC) will have changes to our pharmacy utilization management (UM) requirements. 

Our UM requirements apply to all commercial members with pharmacy benefit coverage through Blue Cross NC. These changes do not affect State Health Plan, Federal Employee Program, Medicare Part D members, or any self-funded employer groups that carve out pharmacy benefits to another pharmacy benefits manager (PBM). 

Below is a summary of the changes, and more details can be found here

NEW REQUIREMENTS 

Carbatrol capsule, Digoxin solution, Dilantin chew/suspension/tablet, Lanoxin tablet, Lithobid tablet, Mysoline tablet, Neoral capsule/solution, Norpace capsule, Phenytek capsule, Prograf capsule, Rapamune tablet/solution, Sandimmune capsule, Tegretol tablet/solution, Tegretol-XR tablet, Zarontin capsul/solution, Zortress tablet – These Brand products with available generic alternatives will require Prior Authorization on the Essential formularies for members new to therapy. Members will be required to trial the generic product prior to the approval of the brand. 

Dymista– This medication and its generic will require Step Therapy on the Essential formularies. The Step Therapy requirement is two over-the-counter intranasal steroid medications.

UPDATED REQUIREMENTS 

Mounjaro 2.5mg injection – Quantity Limit reduced from 8 injections per month to 4 injections per 180 days on all formularies. 

Rybelsus 3mg tablet – Quantity Limit reduced from 1 tablet per day to 30 tablets per 180 days on all formularies. 

FORMULARY CHANGES  

Xiidra 5% Drops – This medication will be removed from all Essential formularies. Members with claims for Xiidra 5% drops in the last 120 days will automatically receive an authorization for Restasis 0.05% single dose vial effective 1/1/2023. 

Brand Vagifem – This medication will be removed from all Essential formularies and the generic version, estradiol 10mg tablet, will be added to formulary as the preferred product.  

Essential 6 Tier (Essential Q) formulary removals 

ARAKODA      TAB 100MG 

AMCINONIDE   LOT 0.1% 

IMBRUVICA 280MG TAB 

KRINTAFEL    TAB 150MG 

LAMICTAL XR  KIT 

NUVESSA      GEL 1.3% 

PRADAXA CAP 150MG 

SUPREP BOWEL SOL PREP KIT 

TAZORAC GEL 0.05% 

TAZORAC GEL 0.1% 

VAGIFEM 

VIIBRYD STARTER PACK 

XIIDRA       DRO 5% 

 

Essential 5 Tier (Essential C) formulary removals 

ACYCLOVIR    OIN 5% 

ADAPAL/BEN P GEL 0.1-2.5% 

ALMOTRIP MAL TAB 12.5MG 

ALMOTRIP MAL TAB 6.25MG 

ALOCRIL      SOL 2% 

ALOMIDE      SOL 0.1% OP 

ALTABAX      OIN 1% 

AMCINONIDE   LOT 0.1% 

AMOXAPINE    TAB 100MG 

AMOXAPINE    TAB 150MG 

AMOXAPINE    TAB 25MG 

AMOXAPINE    TAB 50MG 

APADAZ       TAB 4.08-325 

APADAZ       TAB 6.12-325 

APADAZ       TAB 8.16-325 

ARAKODA      TAB 100MG 

BEPOTASTINE  DRO 1.5% 

BESIVANCE    SUS 0.6% 

BRINZOLAMIDE SUS 1% 

BUPRENORPHIN DIS 10MCG/HR 

BUPRENORPHIN DIS 15MCG/HR 

BUPRENORPHIN DIS 20MCG/HR 

BUPRENORPHIN DIS 5MCG/HR 

BUPRENORPHIN DIS 7.5/HR 

BUSPIRONE    TAB 7.5MG 

CALCIPOTRIEN OIN 0.005% 

CALCITRENE   OIN 0.005% 

CALCITRIOL   OIN 3MCG/GM 

CARISOPRODOL TAB 250MG 

CARISOPRODOL TAB 350MG 

CEFACLOR     SUS 125/5ML 

CEFACLOR     SUS 250/5ML 

CEFACLOR     SUS 375/5ML 

CEPHALEXIN   TAB 250MG 

CIMETIDINE   SOL 300/5ML 

CIMETIDINE   SOL 400MG 

CLOCORTOLONE CRE 0.1% 

CONSENSI     TAB 10-200MG 

CONSENSI     TAB 2.5-200 

CONSENSI     TAB 5-200MG 

DARIFENACIN  TAB 15MG 

DARIFENACIN  TAB 7.5MG 

DESLORATADIN TAB 2.5 ODT 

DESLORATADIN TAB 5MG ODT 

DEXILANT     CAP 30MG DR 

DEXILANT     CAP 60MG DR 

DIFLORASONE  CRE 0.05% 

DIFLUPREDNAT EMU 0.05% 

EPINASTINE   DRO 0.05% 

EPOGEN       INJ 10000/ML 

EPOGEN       INJ 2000/ML 

EPOGEN       INJ 20000/ML 

EPOGEN       INJ 3000/ML 

EPOGEN       INJ 4000/ML 

ERGOLOID MES TAB 1MG ORAL 

ERTACZO      CRE 2% 

ERY/BENZOYL  GEL 3-5% 

EVEKEO ODT   TAB 10MG 

EVEKEO ODT   TAB 5MG 

EXELDERM     SOL 1% 

FEBUXOSTAT   TAB 40MG 

FEBUXOSTAT   TAB 80MG 

FENOPROFEN   TAB 600MG 

FLUOXETINE   TAB 10MG 

FLUVASTATIN  CAP 20MG 

FLUVASTATIN  CAP 40MG 

FROVATRIPTAN TAB 2.5MG 

FULPHILA     INJ 6/0.6ML 

FUROSEMIDE   SOL 8MG/ML 

GRANIX       INJ 300/0.5 

GRANIX       INJ 300/1ML 

GRANIX       INJ 480/0.8 

GRANIX       INJ 480/1.6 

HALDOL DECAN INJ 100MG/ML 

HALDOL DECAN INJ 50MG/ML 

HALOG        OIN 0.1% 

HC BUTYRATE  CRE 0.1% 

HC BUTYRATE  SOL 0.1% 

HYDROCO/APAP TAB 10-300MG 

HYDROCO/APAP TAB 5-300MG 

HYDROCO/APAP TAB 7.5-300 

HYDROCODONE  TAB 100MG ER 

HYDROCODONE  TAB 120MG ER 

HYDROCODONE  TAB 20MG ER 

HYDROCODONE  TAB 30MG ER 

HYDROCODONE  TAB 40MG ER 

HYDROCODONE  TAB 60MG ER 

HYDROCODONE  TAB 80MG ER 

HYDROMORPHON TAB 12MG ER 

HYDROMORPHON TAB 16MG ER 

HYDROMORPHON TAB 32MG ER 

HYDROMORPHON TAB 8MG ER 

ILEVRO       DRO 0.3% OP 

IMBRUVICA 280MG TAB 

IMCIVREE     INJ 10MG/ML 

INFASURF     SUS 35MG/ML 

IRBESAR/HCTZ TAB 150-12.5 

IRBESAR/HCTZ TAB 300-12.5 

KADIAN       CAP 200MG ER 

KETOPROFEN   CAP 200MG ER 

KRINTAFEL    TAB 150MG 

LAMICTAL XR  KIT 

LANSOPR/AMOX MIS /CLARITH 

LANSOPRAZOLE TAB 15MG ODT 

LANSOPRAZOLE TAB 30MG 

LANSOPRAZOLE TAB 30MG ODT 

LASTACAFT    SOL 0.25% 

LEVOCETIRIZI SOL 2.5/5ML 

LEVORPHANOL  TAB 2MG 

LEVORPHANOL  TAB 3MG 

LUBIPROSTONE CAP 24MCG 

LUBIPROSTONE CAP 8MCG 

LUMIGAN      SOL 0.01% 

MAPROTILINE  TAB 25MG 

MAPROTILINE  TAB 50MG 

MAPROTILINE  TAB 75MG 

MECLOFEN SOD CAP 100MG 

MECLOFEN SOD CAP 50MG 

MEPROBAMATE  TAB 200MG 

MEPROBAMATE  TAB 400MG 

METAXALONE   TAB 400MG 

METAXALONE   TAB 800MG 

METHAMPHETAM TAB 5MG 

MORPHINE SUL CAP 40MG ER 

MOZOBIL      INJ 

NAFTIFINE    CRE HCL 1% 

NEBIVOLOL    TAB 10MG 

NEBIVOLOL    TAB 2.5MG 

NEBIVOLOL    TAB 20MG 

NEBIVOLOL    TAB 5MG 

NEFAZODONE   TAB 100MG 

NEFAZODONE   TAB 150MG 

NEFAZODONE   TAB 200MG 

NEFAZODONE   TAB 250MG 

NEFAZODONE   TAB 50MG 

NEULASTA     INJ 6MG/0.6M 

NEULASTA     KIT 6MG/0.6M 

NEUPOGEN     INJ 300/0.5 

NEUPOGEN     INJ 300MCG 

NEUPOGEN     INJ 480/0.8 

NEUPOGEN     INJ 480MCG 

NIZATIDINE   CAP 150MG 

NIZATIDINE   CAP 300MG 

NIZATIDINE   SOL 15MG/ML 

NUVESSA      GEL 1.3% 

NYSTAT/TRIAM CRE 

NYVEPRIA     INJ 6/0.6ML 

OLOPATADINE  SPR 0.6% 

OMEPRA/BICAR POW 20-1680 

OMEPRA/BICAR POW 40-1680 

ONGENTYS     CAP 25MG 

ONGENTYS     CAP 50MG 

OTOVEL       DRO 

OXICONAZOLE  CRE NITRATE 

PEG/NASUL/C/ SOL NACL/POT 

PHOSPHOLINE  SOL 0.125%OP 

PRADAXA CAP 150MG 

PREPIDIL     GEL 0.5MG/3G 

PRILOSEC     POW 10MG 

PRILOSEC     POW 2.5MG 

PROCRIT      INJ 10000/ML 

PROCRIT      INJ 2000/ML 

PROCRIT      INJ 20000/ML 

PROCRIT      INJ 3000/ML 

PROCRIT      INJ 4000/ML 

PROCRIT      INJ 40000/ML 

PROSTIN E2   SUP 20MG 

PSORCON      CRE 0.05% 

RABEPRAZOLE  TAB 20MG 

RAMELTEON    TAB 8MG 

RIBAVIRIN    INH 6GM 

SAVELLA      MIS TITR PAK 

SAVELLA      TAB 100MG 

SAVELLA      TAB 12.5MG 

SAVELLA      TAB 25MG 

SAVELLA      TAB 50MG 

SILODOSIN    CAP 4MG 

SILODOSIN    CAP 8MG 

SOLOSEC      GRA 2GM 

SUPREP BOWEL SOL PREP KIT 

TAZORAC GEL 0.05% 

TAZORAC GEL 0.1% 

TESTOSTERONE GEL 1%(50MG) PACKETS 

TESTOSTERONE GEL PUMP 1% 

THIORIDAZINE TAB 100MG 

THIORIDAZINE TAB 10MG 

THIORIDAZINE TAB 25MG 

THIORIDAZINE TAB 50MG 

TRAVOPROST   DRO 0.004% 

TRIAZOLAM    TAB 0.125MG 

TRIAZOLAM    TAB 0.25MG 

TUZISTRA XR  SUS 

VAGIFEM 

VANADOM      TAB 350MG 

VIIBRYD STARTER PACK 

XIIDRA       DRO 5% 

ZERVIATE     DRO 0.24% 

ZILEUTON ER  TAB 600MG 

ZIRGAN       GEL 0.15% 

ZUBSOLV      SUB 0.7-0.18 

ZUBSOLV      SUB 1.4-0.36 

ZUBSOLV      SUB 11.4-2.9 

ZUBSOLV      SUB 2.9-0.71 

ZUBSOLV      SUB 5.7-1.4 

ZUBSOLV      SUB 8.6-2.1 

 

If you have any questions, please call the Provider Blue LineSM at 1-800-214-4844.